OpenEvidence

OpenEvidence is a medical knowledge platform for healthcare professionals. It answers clinical questions using peer-reviewed research and medical content from NEJM, JAMA and JAMA Network specialty journals, NCCN, and Cochrane. OpenEvidence is an informational aid and does not replace professional clinical judgment.

Key Highlights

• Answers grounded in peer-reviewed medical research
• Full-text clinical findings, figures, tables, and multimedia from NEJM
• Content from JAMA and JAMA Network specialty journals
• NCCN Guidelines treatment algorithms
• Full-text content, figures, tables, and multimedia from Cochrane Systematic Reviews
• A mobile app and HIPAA-compliant service

What Makes It Different

OpenEvidence centers its product on named medical content relationships. It identifies official AI partnerships with The New England Journal of Medicine, JAMA and the JAMA Network specialty journals, a collaboration with NCCN, and a partnership with Cochrane Systematic Reviews.

The distinction is the material included through these relationships. Healthcare professionals can access full-text clinical findings and supporting media from NEJM and JAMA, NCCN treatment algorithms, and Cochrane review content within the platform.

Features & Capabilities

The core capability is evidence-grounded answers for healthcare professionals. The supporting content spans clinical findings, figures, tables, multimedia, systematic reviews, and treatment algorithms from the named publishers and organizations.

OpenEvidence also highlights HIPAA compliance and offers a mobile app for use wherever care happens. Its medical society collaborations include NCCN, ACC, ADA, AAFP, NORD, ACOG, AUA, AAO, and ACEP.

User Ratings and Testimonials

OpenEvidence has a 4.9 out of 5 rating from 11K ratings on the U.S. App Store. Reviewers praise its cited answers, quick evidence lookup, and direct links to journal sources. Critical reviews report server failures during high traffic and warn that broad prompts can return incomplete, misleading, or inaccurate information. Healthcare professionals should review the underlying evidence and apply their own professional clinical judgment.

Pricing & Value

• Verified U.S. healthcare professionals: Free and unlimited access

The free offer is limited to verified U.S. healthcare professionals.